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dc.contributor.authorSoliman, Ibrahim
dc.contributor.authorJohnson, Garrett G. R. J.
dc.contributor.authorGillman, Lawrence M.
dc.contributor.authorZeiler, Frederick A.
dc.contributor.authorFaqihi, Fahad
dc.contributor.authorAletreby, Waleed Tharwat
dc.contributor.authorBalhamar, Abdullah
dc.contributor.authorMahmood, Nasir Nasim
dc.contributor.authorAhmad Mumtaz, Shahzad
dc.contributor.authorAlharthy, Abdulrahman
dc.contributor.authorLazaridis, Christos
dc.contributor.authorKarakitsos, Dimitrios
dc.date.accessioned2018-05-06T07:03:57Z
dc.date.available2018-05-06T07:03:57Z
dc.date.issued2018-04-30
dc.identifier.citationIbrahim Soliman, Garrett G. R. J. Johnson, Lawrence M. Gillman, et al., “New Optic Nerve Sonography Quality Criteria in the Diagnostic Evaluation of Traumatic Brain Injury,” Critical Care Research and Practice, vol. 2018, Article ID 3589762, 7 pages, 2018. doi:10.1155/2018/3589762
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/275595
dc.description.abstractBackground. New sonographic quality criteria to optimize optic nerve sheath diameter (ONSD) measurements were suggested. The latter were correlated to elevated intracranial pressure (ICP) in traumatic brain injury (TBI). Aim. We investigated whether ONSD measurements were correlated to simultaneous ICP measurements in severe TBI. Methods. Forty patients with severe TBI (Marshall Scale ≥II and GCS ≤8) participated in the study. All patients had an intraparenchymal ICP catheter inserted, while ONSD was measured bilaterally, upon admission and over the next 48 hours, based on the new sonographic criteria. A total of 400 ONSD measurements were performed, while mean ONSD values of both eyes were used in the analysis. Results. ONSD measurements were strongly correlated to ICP values (). Receiver operator curve (ROC) analysis revealed that the ONSD cutoff value for predicting elevated ICP was 6.4 mm when using the mean of both eyes (AUC = 0.88, 95% CI = 0.80 to 0.95; sensitivity = 85.3%, specificity = 82.6%). Linear regression analysis nested models revealed that sex () and height () were significant predictors of ONSD values. Conclusion. When applying the new sonographic quality criteria, ONSD is strongly correlated to ICP in severe TBI. Whether to use such criteria to monitor ONSD as a proxy for ICP trend in TBI remains to be further explored.
dc.titleNew Optic Nerve Sonography Quality Criteria in the Diagnostic Evaluation of Traumatic Brain Injury
dc.typeJournal Article
dc.date.updated2018-05-06T07:03:55Z
dc.description.versionPeer Reviewed
dc.language.rfc3066en
dc.rights.holderCopyright © 2018 Ibrahim Soliman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.identifier.doi10.17863/CAM.22842
rioxxterms.versionofrecord10.1155/2018/3589762


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