Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.
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Authors
Al-Ramahi, Ismael
Giridharan, Sai Srinivas Panapakkam
Chen, Yu-Chi
de Haro, Maria
Wagner Gee, Amanda K
Titus, Steven A
Jeong, Hyunkyung
Krainc, Dimitri
Zheng, Wei
Irvine, Robin
Barmada, Sami
Ferrer, Marc
Weisman, Lois S
Botas, Juan
Publication Date
2017-12-26Journal Title
eLife
ISSN
2050-084X
Volume
6
Language
eng
Type
Article
This Version
VoR
Physical Medium
Electronic
Metadata
Show full item recordCitation
Al-Ramahi, I., Giridharan, S. S. P., Chen, Y., Patnaik, S., Safren, N., Hasegawa, J., Hasegawa, J., et al. (2017). Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.. eLife, 6 https://doi.org/10.7554/elife.29123
Keywords
Neurons, Cells, Cultured, Fibroblasts, Animals, Humans, Mice, Drosophila, Huntington Disease, Disease Models, Animal, Phosphotransferases (Alcohol Group Acceptor), Enzyme Inhibitors, Models, Biological, Autophagy, Gene Knockdown Techniques, Proteolysis, Protein Aggregation, Pathological, Huntingtin Protein
Sponsorship
MRC (MR/J001120/1)
Identifiers
External DOI: https://doi.org/10.7554/elife.29123
This record's URL: https://www.repository.cam.ac.uk/handle/1810/276191
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