Repository logo
 

Sequential detection of multiple phase transitions in model biological membranes using a red-emitting conjugated polyelectrolyte.


Change log

Authors

Houston, Judith E 
Kraft, Mario 
Scherf, Ullrich 
Evans, Rachel Claire  ORCID logo  https://orcid.org/0000-0003-2956-4857

Abstract

The anionic conjugated polyelectrolyte, poly[3-(6-sulfothioatehexyl)thiophene] (P3Anionic), functions as a highly sensitive probe of membrane order, uniquely capable of sequentially detecting the three key phase transitions occurring within model phospholipid bilayers. The observed sensitivity is the result of charge-mediated, selective localisation of P3Anionic within the head-groups of the phospholipid bilayer.

Description

Keywords

Cell Membrane, Color, Lipid Bilayers, Models, Molecular, Molecular Conformation, Phase Transition, Polyelectrolytes, Polymers, Spectrometry, Fluorescence, Spectrophotometry, Ultraviolet, Sulfonic Acids, Thiophenes

Journal Title

Phys Chem Chem Phys

Conference Name

Journal ISSN

1463-9076
1463-9084

Volume Title

18

Publisher

Royal Society of Chemistry (RSC)