Alternatives to Traditional Per-Oral Endoscopy for Screening.

Offman, Judith; Fitzgerald, Rebecca C

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Authors

Offman, Judith

Fitzgerald, Rebecca C

Publication Date

2017-07-27

Journal Title

Gastrointestinal Endoscopy Clinics of North America

ISSN

1558-1950

Publisher

Elsevier

Volume

Issue

Pages

379-396

Language

eng

Type

Article

This Version

Metadata

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Citation

Offman, J., & Fitzgerald, R. C. (2017). Alternatives to Traditional Per-Oral Endoscopy for Screening.. Gastrointestinal Endoscopy Clinics of North America, 27 (3), 379-396. https://doi.org/10.1016/j.giec.2017.02.002

Abstract

Barrett's esophagus (BE) predisposes patients to esophageal adenocarcinoma. 3 to 6% of individuals with gastro-esophageal reflux disease are estimated to have BE but only 20 to 25% of BE patients are currently diagnosed. The current gold standard for diagnosis of BE is per-oral upper GI endoscopy. As this is not suitable for large-scale screening, a number of alternative methods are currently being investigated: transnasal and video capsule endoscopy, endomicroscopy, cell collection devices like the cytosponge and biomarkers. Some of these are promising, however, well powered studies carried out in relevant screening populations are needed.

Keywords

Barrett’s esophagus, Biomarkers, Cell collection, Endoscopy, Esophageal adenocarcinoma, Screening, Transnasal endoscopy, Video capsule endoscopy, Adenocarcinoma, Barrett Esophagus, Capsule Endoscopy, Endoscopy, Digestive System, Esophageal Neoplasms, Esophagoscopy, Gastroesophageal Reflux, Humans

Sponsorship

Cancer Research UK (21047)

Identifiers

External DOI: https://doi.org/10.1016/j.giec.2017.02.002

This record's URL: https://www.repository.cam.ac.uk/handle/1810/278395

Rights

Attribution-NonCommercial-NoDerivatives 4.0 International

Licence URL: http://creativecommons.org/licenses/by-nc-nd/4.0/

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