C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.

Lautenschläger, Janin; Stephens, Amberley D; Fusco, Giuliana; Ströhl, Florian; Curry, Nathan; Zacharopoulou, Maria; Michel, Claire; Laine, Romain; Nespovitaya, Nadezhda; Fantham, Marcus; Pinotsi, Dorothea; Zago, Wagner; Fraser, Paul; Tandon, Anurag; St George-Hyslop, Peter; Rees, Eric; Phillips, Jonathan J; De Simone, Alfonso; Kaminski, Clemens; Schierle, Gabriele S Kaminski

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Authors

Lautenschläger, Janin

Stephens, Amberley D

Fusco, Giuliana

Ströhl, Florian

Curry, Nathan

Zacharopoulou, Maria

Michel, Claire

Publication Date

2018-02-19

Journal Title

Nature communications

ISSN

2041-1723

Volume

Issue

Pages

712

Language

eng

Type

Article

This Version

VoR

Physical Medium

Electronic

Metadata

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Citation

Lautenschläger, J., Stephens, A. D., Fusco, G., Ströhl, F., Curry, N., Zacharopoulou, M., Michel, C., et al. (2018). C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.. Nature communications, 9 (1), 712. https://doi.org/10.1038/s41467-018-03111-4

Keywords

Presynaptic Terminals, Synaptic Vesicles, Cell Line, Synaptosomes, Animals, Humans, Rats, Rats, Sprague-Dawley, Calcium, Microscopy, Electron, Transmission, Nuclear Magnetic Resonance, Biomolecular, Binding Sites, Protein Binding, Lipid Metabolism, alpha-Synuclein, In Vitro Techniques, Protein Aggregates

Sponsorship

MRC (MR/K02292X/1)

Alzheimer's Research UK (ARUK-PG2013-14)

BBSRC (BB/H023917/1)

EPSRC (EP/H018301/1)

MRC (G0902243)

Identifiers

External DOI: https://doi.org/10.1038/s41467-018-03111-4

This record's URL: https://www.repository.cam.ac.uk/handle/1810/278584

Rights

Attribution 4.0 International

Licence URL: http://creativecommons.org/licenses/by/4.0/

The following licence files are associated with this item:

Creative Commons

Except where otherwise noted, this item's licence is described as Attribution 4.0 International