Dendritic Ca<sup>2+</sup> dynamics and multimodal processing in a cricket antennal interneuron.
Bayley, Timothy George
Journal of neurophysiology
American Physiological Society
MetadataShow full item record
Bayley, T. G., & Hedwig, B. (2018). Dendritic Ca<sup>2+</sup> dynamics and multimodal processing in a cricket antennal interneuron.. Journal of neurophysiology, 120 (3), 910-919. https://doi.org/10.1152/jn.00663.2017
The integration of stimuli of different modalities is fundamental to information processing within the nervous system. A descending interneuron in the cricket brain, with prominent dendrites in the deutocerebrum, receives input from three sensory modalities: touch of the antennal flagellum, strain of the antennal base, and visual stimulation. Using calcium imaging, we demonstrate that each modality drives a Ca2+ increase in a different dendritic region. Moreover, touch of the flagellum is represented in a topographic map along the neuron’s dendrites. Using intracellular recording, we investigated the effects of Ca2+ on spike shape through the application of the Ca2+ channel antagonist, Cd2+, and identified probable Ca2+-dependent K+ currents.
Brain, Dendrites, Interneurons, Flagella, Animals, Gryllidae, Calcium, Cadmium, Calcium Channels, Potassium Channels, Calcium-Activated, Calcium Channel Blockers, Photic Stimulation, Touch, Calcium Signaling, Action Potentials, Female, Male, Arthropod Antennae, Optical Imaging
PhD studentship of MRCUK
External DOI: https://doi.org/10.1152/jn.00663.2017
This record's URL: https://www.repository.cam.ac.uk/handle/1810/279339