Alcohol consumption and future hospital usage: The EPIC-Norfolk prospective population study.
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Authors
Hayat, Shabina
Mulligan, Angela
Wareham, Nicholas
Khaw, Kay-Tee
Publication Date
2018Journal Title
PLoS One
ISSN
1932-6203
Publisher
Public Library of Science (PLoS)
Volume
13
Issue
7
Pages
e0200747
Language
eng
Type
Article
Physical Medium
Electronic-eCollection
Metadata
Show full item recordCitation
Luben, R., Hayat, S., Mulligan, A., Lentjes, M., Wareham, N., Pharoah, P., & Khaw, K. (2018). Alcohol consumption and future hospital usage: The EPIC-Norfolk prospective population study.. PLoS One, 13 (7), e0200747. https://doi.org/10.1371/journal.pone.0200747
Abstract
BACKGROUND: Heavy drinkers of alcohol are reported to use hospitals more than non-drinkers, but it is unclear whether light-to-moderate drinkers use hospitals more than non-drinkers. OBJECTIVE: We examined the relationship between alcohol consumption in 10,883 men and 12,857 women aged 40-79 years in the general population and subsequent admissions to hospital and time spent in hospital. METHODS: Participants from the EPIC-Norfolk prospective population-based study were followed for ten years (1999-2009) using record linkage. RESULTS: Compared to current non-drinkers, men who reported any alcohol drinking had a lower risk of spending more than twenty days in hospital multivariable adjusted OR 0.80 (95%CI 0.68-0.94) after adjusting for age, smoking status, education, social class, body mass index and prevalent diseases. Women who were current drinkers were less likely to have any hospital admissions multivariable adjusted OR 0.84 (95%CI 0.74-0.95), seven or more admissions OR 0.77 (95% CI 0.66-0.88) or more than twenty hospital days OR 0.70 (95%CI 0.62-0.80). However, compared to lifelong abstainers, men who were former drinkers had higher risk of any hospital admissions multivariable adjusted OR 2.22 (95%CI 1.51-3.28) and women former drinkers had higher risk of seven or more admissions OR 1.30 (95%CI 1.01-1.67). CONCLUSION: Current alcohol consumption was associated with lower risk of future hospital usage compared with non-drinkers in this middle aged and older population. In men, this association may in part be due to whether former drinkers are included in the non-drinker reference group but in women, the association was consistent irrespective of the choice of reference group. In addition, there were few participants in this cohort with very high current alcohol intake. The measurement of past drinking, the separation of non-drinkers into former drinkers and lifelong abstainers and the choice of reference group are all influential in interpreting the risk of alcohol consumption on future hospitalisation.
Keywords
Adult, Aged, Alcohol Drinking, Female, Hospitalization, Humans, Logistic Models, Male, Middle Aged, Prospective Studies, Risk Factors
Sponsorship
Medical Research Council (G1000143)
Cancer Research Uk (None)
Medical Research Council (MR/N003284/1)
Medical Research Council (MC_UU_12015/1)
Department of Health (via National Institute for Health Research (NIHR)) (NF-SI-0617-10149)
Department of Health (via National Institute for Health Research (NIHR)) (NF-SI-0512-10135)
Medical Research Council (G0401527)
Cancer Research Uk (None)
Cancer Research Uk (None)
Identifiers
External DOI: https://doi.org/10.1371/journal.pone.0200747
This record's URL: https://www.repository.cam.ac.uk/handle/1810/279605
Rights
Attribution 4.0 International (CC BY 4.0)
Licence URL: https://creativecommons.org/licenses/by/4.0/
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