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dc.contributor.authorYücel, Murat
dc.contributor.authorOldenhof, Erin
dc.contributor.authorAhmed, Serge H
dc.contributor.authorBelin, David
dc.contributor.authorBillieux, Joel
dc.contributor.authorBowden-Jones, Henrietta
dc.contributor.authorCarter, Adrian
dc.contributor.authorChamberlain, Samuel
dc.contributor.authorClark, Luke
dc.contributor.authorConnor, Jason
dc.contributor.authorDaglish, Mark
dc.contributor.authorDom, Geert
dc.contributor.authorDannon, Pinhas
dc.contributor.authorDuka, Theodora
dc.contributor.authorFernandez-Serrano, Maria Jose
dc.contributor.authorField, Matt
dc.contributor.authorFranken, Ingmar
dc.contributor.authorGoldstein, Rita Z
dc.contributor.authorGonzalez, Raul
dc.contributor.authorGoudriaan, Anna E
dc.contributor.authorGrant, Jon E
dc.contributor.authorGullo, Matthew J
dc.contributor.authorHester, Robert
dc.contributor.authorHodgins, David C
dc.contributor.authorLe Foll, Bernard
dc.contributor.authorLee, Rico SC
dc.contributor.authorLingford-Hughes, Anne
dc.contributor.authorLorenzetti, Valentina
dc.contributor.authorMoeller, Scott J
dc.contributor.authorMunafò, Marcus R
dc.contributor.authorOdlaug, Brian
dc.contributor.authorPotenza, Marc N
dc.contributor.authorSegrave, Rebecca
dc.contributor.authorSjoerds, Zsuzsika
dc.contributor.authorSolowij, Nadia
dc.contributor.authorvan den Brink, Wim
dc.contributor.authorvan Holst, Ruth J
dc.contributor.authorVoon, Valerie
dc.contributor.authorWiers, Reinout
dc.contributor.authorFontenelle, Leonardo F
dc.contributor.authorVerdejo-Garcia, Antonio
dc.date.accessioned2018-09-08T06:34:51Z
dc.date.available2018-09-08T06:34:51Z
dc.date.issued2019-06
dc.identifier.issn0965-2140
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/279925
dc.description.abstractBACKGROUND: The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal of improving diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the 'primary' RDoC constructs most relevant to substance and behavioural addictions. METHODS: Forty-four addiction experts were recruited from Australia, Asia, Europe and the Americas. The Delphi technique was used to determine a consensus as to the degree of importance of each construct in understanding the essential dimensions underpinning addictive behaviours. Expert opinions were canvassed online over three rounds (97% completion rate), with each consecutive round offering feedback for experts to review their opinions. RESULTS: Seven constructs were endorsed by ≥ 80% of experts as 'primary' to the understanding of addictive behaviour: five from the Positive Valence System (reward valuation, expectancy, action selection, reward learning, habit); one from the Cognitive Control System (response selection/inhibition); and one expert-initiated construct (compulsivity). These constructs were rated to be related differentially to stages of the addiction cycle, with some linked more closely to addiction onset and others more to chronicity. Experts agreed that these neuropsychological dimensions apply across a range of addictions. CONCLUSIONS: The study offers a novel and neuropsychologically informed theoretical framework, as well as a cogent step forward to test transdiagnostic concepts in addiction research, with direct implications for assessment, diagnosis, staging of disorder, and treatment.
dc.description.sponsorshipMedical research Council Leverhulme Trust
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherWiley
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectHumans
dc.subjectSubstance-Related Disorders
dc.subjectHabits
dc.subjectCompulsive Behavior
dc.subjectBehavior, Addictive
dc.subjectLearning
dc.subjectReward
dc.subjectDecision Making
dc.subjectNational Institute of Mental Health (U.S.)
dc.subjectDelphi Technique
dc.subjectNorth America
dc.subjectUnited States
dc.subjectSouth America
dc.subjectAsia
dc.subjectAustralia
dc.subjectEurope
dc.subjectInhibition, Psychological
dc.titleA transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study.
dc.typeArticle
prism.endingPage1109
prism.issueIdentifier6
prism.publicationDate2019
prism.publicationNameAddiction
prism.startingPage1095
prism.volume114
dc.identifier.doi10.17863/CAM.27293
dcterms.dateAccepted2018-08-14
rioxxterms.versionofrecord10.1111/add.14424
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2019-06
dc.contributor.orcidYücel, Murat [0000-0002-4705-452X]
dc.contributor.orcidAhmed, Serge H [0000-0002-1225-9234]
dc.contributor.orcidBelin, David [0000-0002-7383-372X]
dc.contributor.orcidBillieux, Joel [0000-0002-7388-6194]
dc.contributor.orcidCarter, Adrian [0000-0002-3593-0772]
dc.contributor.orcidChamberlain, Samuel [0000-0001-7014-8121]
dc.contributor.orcidClark, Luke [0000-0003-1103-2422]
dc.contributor.orcidDaglish, Mark [0000-0002-1787-4375]
dc.contributor.orcidGoudriaan, Anna E [0000-0001-8670-9384]
dc.contributor.orcidGrant, Jon E [0000-0001-7784-7021]
dc.contributor.orcidGullo, Matthew J [0000-0003-3657-5191]
dc.contributor.orcidHester, Robert [0000-0003-0982-8026]
dc.contributor.orcidHodgins, David C [0000-0003-2737-5200]
dc.contributor.orcidLe Foll, Bernard [0000-0002-6406-4973]
dc.contributor.orcidLingford-Hughes, Anne [0000-0003-4512-3453]
dc.contributor.orcidMoeller, Scott J [0000-0002-4449-0844]
dc.contributor.orcidMunafò, Marcus R [0000-0002-4049-993X]
dc.contributor.orcidOdlaug, Brian [0000-0001-5407-0686]
dc.contributor.orcidSjoerds, Zsuzsika [0000-0001-9467-3772]
dc.contributor.orcidSolowij, Nadia [0000-0002-5222-5637]
dc.contributor.orcidVoon, Valerie [0000-0001-6790-1776]
dc.contributor.orcidWiers, Reinout [0000-0002-4312-9766]
dc.contributor.orcidVerdejo-Garcia, Antonio [0000-0001-8874-9339]
dc.identifier.eissn1360-0443
rioxxterms.typeJournal Article/Review
pubs.funder-project-idLeverhulme Trust (RPG-2016-117)
pubs.funder-project-idMedical Research Council (MR/N02530X/1)
pubs.funder-project-idWellcome Trust (110049/Z/15/Z)
pubs.funder-project-idMedical Research Council (MR/P008747/1)
cam.issuedOnline2018-10-05
cam.orpheus.successThu Jan 30 10:54:39 GMT 2020 - The item has an open VoR version.
rioxxterms.freetoread.startdate2100-01-01


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International