Adaptive coding in the human brain: Distinct object features are encoded by overlapping voxels in frontoparietal cortex.
Jackson, Jade B
MetadataShow full item record
Jackson, J. B., & Woolgar, A. (2018). Adaptive coding in the human brain: Distinct object features are encoded by overlapping voxels in frontoparietal cortex.. Cortex, 108 25-34. https://doi.org/10.1016/j.cortex.2018.07.006
Our ability to flexibly switch between different tasks is a key component of cognitive control. Non-human primate (NHP) studies (e.g., Freedman, Riesenhuber, Poggio, & Miller, 2001) have shown that prefrontal neurons are re-used across tasks, re-configuring their responses to code currently relevant information. In a similar vein, in the human brain, the "multiple demand" (MD) system is suggested to exert control by adjusting its responses, selectively processing information in line with our current goals (Duncan, 2010). However, whether the same or different resources (underlying neural populations) in the human brain are recruited to solve different tasks remains elusive. In the present study, we aimed to bridge the gap between the NHP and human literature by examining human functional imaging data at an intermediate level of resolution: quantifying the extent to which single voxels contributed to multiple neural codes. Participants alternated between two tasks requiring the selection of feature information from two distinct sets of objects. We examined whether neural codes for the relevant stimulus features in the two different tasks depended on the same or different voxels. In line with the electrophysiological literature, MD voxels were more likely to contribute to multiple neural codes than we predicted based on permutation tests. Comparatively, in the visual system the neural codes depended on distinct sets of voxels. Our data emphasise the flexibility of the MD regions to re-configure their responses and adaptively code relevant information across different tasks.
Adaptive coding, MVPA, Voxel re-use, fMRI, Adult, Attention, Brain Mapping, Female, Frontal Lobe, Functional Neuroimaging, Humans, Magnetic Resonance Imaging, Male, Parietal Lobe, Visual Perception, Young Adult
Medical Research Council (MC_UU_00005/17)
External DOI: https://doi.org/10.1016/j.cortex.2018.07.006
This record's URL: https://www.repository.cam.ac.uk/handle/1810/279951
Attribution 4.0 International (CC BY 4.0)
Licence URL: https://creativecommons.org/licenses/by/4.0/
Recommended or similar items
The current recommendation prototype on the Apollo Repository will be turned off on 03 February 2023. Although the pilot has been fruitful for both parties, the service provider IKVA is focusing on horizon scanning products and so the recommender service can no longer be supported. We recognise the importance of recommender services in supporting research discovery and are evaluating offerings from other service providers. If you would like to offer feedback on this decision please contact us on: email@example.com