Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential.

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Authors
Rubinsztein, DC
Frake, RA
Publication Date
2016-12
Journal Title
J R Coll Physicians Edinb
ISSN
1478-2715
Publisher
SAGE Publications
Volume
46
Issue
4
Pages
228-233
Language
eng
Type
Article
Physical Medium
Print
Metadata
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Citation
Rubinsztein, D., & Frake, R. (2016). Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential.. J R Coll Physicians Edinb, 46 (4), 228-233. https://doi.org/10.4997/jrcpe.2016.403
Abstract
On 3 October 2016, Japanese cell biologist Yoshinori Ohsumi was awarded the Nobel Prize in Physiology or Medicine 'for his discoveries of mechanisms for autophagy'; autophagy being an intracellular degradation pathway that helps maintain cytoplasmic homeostasis. This commentary discusses Ohsumi's Nobel prize-winning work in context, before explaining the clinical relevance of autophagy.
Keywords
Yoshinori Ohsumi, autophagy, yeast genetics, Autophagy, History, 20th Century, Homeostasis, Humans, Medicine, Nobel Prize, Physiology
Identifiers
External DOI: https://doi.org/10.4997/jrcpe.2016.403
This record's URL: https://www.repository.cam.ac.uk/handle/1810/280188
Rights
Licence:
http://www.rioxx.net/licenses/all-rights-reserved
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