Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential.
The journal of the Royal College of Physicians of Edinburgh
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Rubinsztein, D., & Frake, R. (2016). Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential.. The journal of the Royal College of Physicians of Edinburgh, 46 (4), 228-233. https://doi.org/10.4997/jrcpe.2016.403
On 3 October 2016, Japanese cell biologist Yoshinori Ohsumi was awarded the Nobel Prize in Physiology or Medicine 'for his discoveries of mechanisms for autophagy'; autophagy being an intracellular degradation pathway that helps maintain cytoplasmic homeostasis. This commentary discusses Ohsumi's Nobel prize-winning work in context, before explaining the clinical relevance of autophagy.
Humans, Physiology, Medicine, Homeostasis, Nobel Prize, History, 20th Century, Autophagy
External DOI: https://doi.org/10.4997/jrcpe.2016.403
This record's URL: https://www.repository.cam.ac.uk/handle/1810/280188