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dc.contributor.authorRintoul, Robert C
dc.contributor.authorGlover, Matthew J
dc.contributor.authorJackson, Christopher
dc.contributor.authorHughes, Victoria
dc.contributor.authorTournoy, Kurt G
dc.contributor.authorDooms, Christophe
dc.contributor.authorAnnema, Jouke T
dc.contributor.authorSharples, Linda D
dc.date.accessioned2018-09-11T17:32:41Z
dc.date.available2018-09-11T17:32:41Z
dc.date.issued2014-07
dc.identifier.issn0040-6376
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/280206
dc.description.abstractIn the ASTER study, mediastinal staging was more accurate for patients randomised to combined endobronchial and endoscopic ultrasound, followed by surgical staging if endoscopy was negative, versus surgical staging alone. Here, we report survival, quality of life and cost effectiveness up to 6 months, for the UK, The Netherlands and Belgium, separately. Survival in the two arms of the study was similar. In all three countries, the endosonography strategy had slightly higher quality-adjusted life years over 6 months, and was cheaper. Therefore, based on clinical accuracy and cost effectiveness, we conclude that mediastinal staging should commence with endosonography.
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherBMJ
dc.subjectHumans
dc.subjectLung Neoplasms
dc.subjectLymphatic Metastasis
dc.subjectPostoperative Complications
dc.subjectPositron-Emission Tomography
dc.subjectTomography, X-Ray Computed
dc.subjectEndosonography
dc.subjectNeoplasm Staging
dc.subjectPneumonectomy
dc.subjectSurvival Rate
dc.subjectBayes Theorem
dc.subjectSensitivity and Specificity
dc.subjectProspective Studies
dc.subjectQuality of Life
dc.subjectCost-Benefit Analysis
dc.subjectBelgium
dc.subjectNetherlands
dc.subjectFemale
dc.subjectMale
dc.subjectUnited Kingdom
dc.titleCost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective.
dc.typeArticle
prism.endingPage681
prism.issueIdentifier7
prism.publicationDate2014
prism.publicationNameThorax
prism.startingPage679
prism.volume69
dc.identifier.doi10.17863/CAM.27573
rioxxterms.versionofrecord10.1136/thoraxjnl-2013-204374
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2014-07
dc.contributor.orcidRintoul, Robert [0000-0003-3875-3780]
dc.contributor.orcidJackson, Christopher [0000-0002-6656-8913]
dc.identifier.eissn1468-3296
rioxxterms.typeJournal Article/Review
cam.issuedOnline2013-09-24
rioxxterms.freetoread.startdate2015-07-31


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