Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury.

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Authors
  Dickens, Alex M
  Posti, Jussi P
Takala, Riikka SK
  Ala-Seppälä, Henna
Mattila, Ismo
  Coles, Jonathan
Frantzén, Janek
Publication Date
2018-11
Journal Title
Journal of neurotrauma
ISSN
0897-7151
Publisher
Mary Ann Liebert
Volume
35
Issue
22
Pages
2673-2683
Language
eng
Type
Article
Physical Medium
Print-Electronic
Metadata
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Citation
Dickens, A. M., Posti, J. P., Takala, R. S., Ala-Seppälä, H., Mattila, I., Coles, J., Frantzén, J., et al. (2018). Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury.. Journal of neurotrauma, 35 (22), 2673-2683. https://doi.org/10.1089/neu.2017.5272
Abstract
There is a need to rapidly detect patients with traumatic brain injury (TBI) who require head computed tomography (CT). Given the energy crisis in the brain following TBI, we hypothesised that serum metabolomics would be a useful tool for developing a set of biomarkers to determine the need for CT and to distinguish between different types of injuries observed.
Keywords
Humans, Tomography, X-Ray Computed, Adolescent, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Young Adult, Biomarkers, Brain Injuries, Traumatic
Sponsorship
EU FP7 project TBIcare - Project ref. 270259 NIHR Cambridge Biomedical Research Centre
Funder references
Cambridge University Hospitals NHS Foundation Trust (CUH) (unknown)
Cambridge University Hospitals NHS Foundation Trust (CUH) (146281)
Academy of Medical Sciences (unknown)
MRC (G1002277)
MRC (G0601025)
MRC (G0600986)
MRC (G9439390)
Identifiers
External DOI: https://doi.org/10.1089/neu.2017.5272
This record's URL: https://www.repository.cam.ac.uk/handle/1810/282788

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