AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
Randall, Ricardo S
Melnyk, Charles W
Mähönen, Ari Pekka
Murray, James AH
The Company of Biologists
MetadataShow full item record
Randall, R. S., Miyashima, S., Blomster, T., Zhang, J., Elo, A., Karlberg, A., Immanen, J., et al. (2015). AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.. Biol Open, 4 (10), 1229-1236. https://doi.org/10.1242/bio.013128
Higher plant vasculature is characterized by two distinct developmental phases. Initially, a well-defined radial primary pattern is established. In eudicots, this is followed by secondary growth, which involves development of the cambium and is required for efficient water and nutrient transport and wood formation. Regulation of secondary growth involves several phytohormones, and cytokinins have been implicated as key players, particularly in the activation of cell proliferation, but the molecular mechanisms mediating this hormonal control remain unknown. Here we show that the genes encoding the transcription factor AINTEGUMENTA (ANT) and the D-type cyclin CYCD3;1 are expressed in the vascular cambium of Arabidopsis roots, respond to cytokinins and are both required for proper root secondary thickening. Cytokinin regulation of ANT and CYCD3 also occurs during secondary thickening of poplar stems, suggesting this represents a conserved regulatory mechanism.
Biotechnology and Biological Sciences Research Council (BB/D011914/1)
Biotechnology and Biological Sciences Research Council (BB/E024858/1)
External DOI: https://doi.org/10.1242/bio.013128
This record's URL: https://www.repository.cam.ac.uk/handle/1810/282923
Attribution 4.0 International
Licence URL: https://creativecommons.org/licenses/by/4.0/