Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells.

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Authors
  Trifunov, Selena
Pyle, Angela
Valentino, Maria Lucia
Liguori, Rocco
Yu Wai Man, Patrick
Burté, Florence
Duff, Jennifer
Publication Date
2018-08-03
Journal Title
Scientific reports
ISSN
2045-2322
Volume
8
Issue
1
Pages
11682
Language
eng
Type
Article
Physical Medium
Electronic
Metadata
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Citation
Trifunov, S., Pyle, A., Valentino, M. L., Liguori, R., Yu Wai Man, P., Burté, F., Duff, J., et al. (2018). Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells.. Scientific reports, 8 (1), 11682. https://doi.org/10.1038/s41598-018-30143-z
Keywords
Muscle Cells, Humans, Electron Transport Complex IV, Succinate Dehydrogenase, GTP Phosphohydrolases, DNA, Mitochondrial, Biopsy, Reproducibility of Results, Polymerase Chain Reaction, Sequence Deletion, Oxidative Phosphorylation, Gene Dosage, Genes, Recessive, Mutation, Adolescent, Adult, Aged, Middle Aged, Female, Male, Muscle Fibers, Skeletal, Young Adult
Sponsorship
Wellcome Trust (109915_A_15_Z)
MRC (MR/N025431/2)
Identifiers
External DOI: https://doi.org/10.1038/s41598-018-30143-z
This record's URL: https://www.repository.cam.ac.uk/handle/1810/283111

Rights
Attribution 4.0 International
Licence URL: https://creativecommons.org/licenses/by/4.0/

Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International