Cancer development: Origins in the oesophagus.
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Publication Date
2017-10-26Journal Title
Nature
ISSN
0028-0836
Publisher
Springer Science and Business Media LLC
Volume
550
Issue
7677
Pages
463-464
Language
eng
Type
Article
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
Zhuang, L., & Fitzgerald, R. (2017). Cancer development: Origins in the oesophagus.. Nature, 550 (7677), 463-464. https://doi.org/10.1038/nature24150
Abstract
The cellular origins of a precancerous condition called Barrett's oesophagus have been unclear. Tracking and analysis of epithelial cells at the affected site could shed light on the problem. See Letter p.529
A precancerous condition called Barrett's oesophagus is of much interest, because it arises when some cells of the oesophagus take on a new identity — a phenomenon known as metaplasia. If we could understand where these altered cells come from, we might hold the key to preventing oesophageal cancer. On page 529, Jiang et al.1 provide fresh insight into the cell of origin for Barrett's oesophagus.
Keywords
Humans, Adenocarcinoma, Esophageal Neoplasms
Sponsorship
Medical Research Council (MC_UU_12022/2)
Identifiers
External DOI: https://doi.org/10.1038/nature24150
This record's URL: https://www.repository.cam.ac.uk/handle/1810/284186
Rights
Licence:
http://www.rioxx.net/licenses/all-rights-reserved
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