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dc.contributor.authorRoman-Urrestarazu, Andres
dc.contributor.authorAli, Faleh Mohamed Hussain
dc.contributor.authorReka, Husein
dc.contributor.authorRenwick, Matthew J
dc.contributor.authorRoman, Gabriela
dc.contributor.authorMossialos, Elias
dc.date.accessioned2018-11-05T10:26:07Z
dc.date.available2018-11-05T10:26:07Z
dc.date.issued2016
dc.identifier.issn2052-4897
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/284612
dc.description.abstractAIMS: Understanding type 2 diabetes mellitus is critical for designing effective diabetes prevention policies in Qatar and the Middle East. METHODS: Using the Qatar 2012 WHO STEPwise approach to surveillance survey, a subsample of 1224 Qatari participants aged 18-64 years was selected. Subjects had their fasting blood glucose levels tested, had not been diagnosed with or treated for diabetes, had a fasting time >12 hours and were not pregnant. We applied a hypothesized structural equation model (SEM) to assess sociodemographic, behavioral, anthropometric and metabolic variables affecting persons with type 2 diabetes mellitus. RESULTS: There is a direct effect of triglyceride levels (0.336) and body mass index (BMI) (0.164) on diabetes status. We also found that physical activity levels negatively affect BMI (-0.148) and positively affect high-density lipoprotein (HDL) (0.106); sociodemographic background negatively affects diet (-0.522) and BMI (-0.352); HDL positively affects total cholesterol (0.230) and has a negative effect on BMI (-0.108), triglycerides (-0.128) and waist circumference (-0.104). Diet has a positive effect on triglycerides (0.281) while family history of diabetes negatively affects total cholesterol (-0.104). BMI has a positive effect on waist circumference (0.788) and mediates the effects of physical activity over diabetes status (-0.028). BMI also mediates the effects that sociodemographic factors (-0.058) and physical activity (-0.024) have on diabetes status. BMI and HDL (-0.002) together mediate the effect of physical activity on diabetes status and similarly HDL and tryglycerides (-0.005) also mediate the effect of physical activity on diabetes status. Finally diet and tryglycerides mediate the effects that sociodemographic factors have on diabetes status (-0.049). CONCLUSIONS: This study's main finding is that triglyceride levels and BMI are the main variables directly affecting diabetes status in the Qatari population.
dc.format.mediumElectronic-eCollection
dc.languageeng
dc.publisherBMJ
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.titleStructural equation model for estimating risk factors in type 2 diabetes mellitus in a Middle Eastern setting: evidence from the STEPS Qatar.
dc.typeArticle
prism.issueIdentifier1
prism.publicationDate2016
prism.publicationNameBMJ Open Diabetes Res Care
prism.startingPagee000231
prism.volume4
dc.identifier.doi10.17863/CAM.31986
dcterms.dateAccepted2016-07-21
rioxxterms.versionofrecord10.1136/bmjdrc-2016-000231
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2016-01
dc.contributor.orcidRoman-Urrestarazu, Andres [0000-0002-2405-9432]
dc.identifier.eissn2052-4897
rioxxterms.typeJournal Article/Review
pubs.funder-project-idGillings Family Foundation
cam.issuedOnline2016-09-29


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Attribution-NonCommercial 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial 4.0 International