Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study
Authors
van Veen, Ernest
van der Jagt, Mathieu
Cnossen, Maryse C
Maas, Andrew I R
de Beaufort, Inez D
Menon, David K
Citerio, Giuseppe
Stocchetti, Nino
Rietdijk, Wim J R
van Dijck, Jeroen T J M
Kompanje, Erwin J O
Publication Date
2018-11-16Type
Journal Article
Metadata
Show full item recordCitation
van Veen, E., van der Jagt, M., Cnossen, M. C., Maas, A. I. R., de Beaufort, I. D., Menon, D. K., Citerio, G., et al. (2018). Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study. [Journal Article]. https://doi.org/10.1186/s13054-018-2241-4
Abstract
Abstract
Background
We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation.
Methods
Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study centers completed several questionnaires (response rate: 99%).
Results
Regarding practices around brain death, we found agreement on the clinical evaluation (prerequisites and neurological assessment) for brain death determination (BDD) in 100% of the centers. However, ancillary tests were required for BDD in 64% of the centers. BDD for nondonor patients was deemed mandatory in 18% of the centers before withdrawing life-sustaining measures (LSM). Also, practices around postmortem organ donation varied. Organ donation after circulatory arrest was forbidden in 45% of the centers. When withdrawal of LSM was contemplated, in 67% of centers the patients with a ventricular drain in situ had this removed, either sometimes or all of the time.
Conclusions
This study showed both agreement and some regional differences regarding practices around brain death and postmortem organ donation. We hope our results help quantify and understand potential differences, and provide impetus for current dialogs toward further harmonization of practices around brain death and postmortem organ donation.
Identifiers
External DOI: https://doi.org/10.1186/s13054-018-2241-4
This record's DOI: https://doi.org/10.17863/CAM.32761
Rights
Rights Holder: The Author(s).
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