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dc.contributor.authorCrespin, Lorene
dc.contributor.authorGreb, Andreas
dc.contributor.authorBlakemore, David C
dc.contributor.authorLey, Steven
dc.date.accessioned2018-11-19T14:22:24Z
dc.date.available2018-11-19T14:22:24Z
dc.date.issued2017-12-15
dc.identifier.issn1520-6904
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285414
dc.description.abstractA visible-light-mediated annulation of N-sulfonylallylamines and olefins is reported. Rapid access to highly functionalized chloromethylated pyrrolidines can be achieved using mild conditions for the generation of nitrogen-centered radicals. Both a transition-metal-based catalyst and an organic dye can be used as photosensitizers with 0.5 mol % loading. The reaction was found to be applicable to a large variety of electron-rich and electron-neutral olefins.
dc.description.sponsorshipThis work was supported by a postdoctoral fellowship from Pfizer (L.C. and A.G.) and the EPSRC Grants EP/K009494/1 and EP/M004120/1 (S.V.L.).
dc.languageeng
dc.publisherAmerican Chemical Society (ACS)
dc.titleVisible-Light-Mediated Annulation of Electron-Rich Alkenes and Nitrogen-Centered Radicals from N-Sulfonylallylamines: Construction of Chloromethylated Pyrrolidine Derivatives.
dc.typeArticle
prism.endingPage13108
prism.issueIdentifier24
prism.publicationDate2017
prism.publicationNameJournal of Organic Chemistry
prism.startingPage13093
prism.volume82
dc.identifier.doi10.17863/CAM.32776
dcterms.dateAccepted2017-11-09
rioxxterms.versionofrecord10.1021/acs.joc.7b02146
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2017-12-15
dc.contributor.orcidCrespin, Lorene [0000-0002-7491-7538]
dc.contributor.orcidLey, Steven [0000-0002-7816-0042]
dc.identifier.eissn1520-6904
rioxxterms.typeJournal Article/Review
pubs.funder-project-idEngineering and Physical Sciences Research Council (EP/M004120/1)
pubs.funder-project-idEngineering and Physical Sciences Research Council (EP/K009494/1)
cam.issuedOnline2017-11-09


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