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dc.contributor.authorDas, Debasishen
dc.contributor.authorLauga, Eric Laugaen
dc.date.accessioned2018-11-20T00:31:19Z
dc.date.available2018-11-20T00:31:19Z
dc.date.issued2018-07en
dc.identifier.issn1744-683X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285470
dc.description.abstractThe rotary motor of bacteria is a natural nano-technological marvel that enables cell locomotion by powering the rotation of semi-rigid helical flagellar filaments in fluid environments. It is well known that the motor operates essentially at constant torque in counter-clockwise direction but past work have reported a large range of values of this torque. Focusing on Escherichia coli cells that are swimming and cells that are stuck on a glass surface for which all geometrical and environmental parameters are known (N. C. Darnton et al., J. Bacteriol., 2007, 189, 1756-1764), we use two validated numerical methods to compute the value of the motor torque consistent with experiments. Specifically, we use (and compare) a numerical method based on the boundary integral representation of Stokes flow and also develop a hybrid method combining boundary element and slender body theory to model the cell body and flagellar filament, respectively. Using measured rotation speed of the motor, our computations predict a value of the motor torque in the range 440 pN nm to 829 pN nm, depending critically on the distance between the flagellar filaments and the nearby surface.
dc.format.mediumPrinten
dc.languageengen
dc.subjectEscherichia colien
dc.subjectGlassen
dc.subjectMovementen
dc.subjectSwimmingen
dc.subjectTorqueen
dc.subjectModels, Biologicalen
dc.titleComputing the motor torque of Escherichia coli.en
dc.typeArticle
prism.endingPage5967
prism.issueIdentifier29en
prism.publicationDate2018en
prism.publicationNameSoft matteren
prism.startingPage5955
prism.volume14en
dc.identifier.doi10.17863/CAM.32828
dcterms.dateAccepted2018-06-02en
rioxxterms.versionofrecord10.1039/c8sm00536ben
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2018-07en
dc.contributor.orcidDas, Debasish [0000-0003-2365-4720]
dc.contributor.orcidLauga, Eric [0000-0002-8916-2545]
dc.identifier.eissn1744-6848
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idECH2020 EUROPEAN RESEARCH COUNCIL (ERC) (682754)
rioxxterms.freetoread.startdate2019-07-31


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