Show simple item record

dc.contributor.authorPalatini, Paolo
dc.contributor.authorRosei, Enrico Agabiti
dc.contributor.authorAvolio, Alberto
dc.contributor.authorBilo, Gregorz
dc.contributor.authorCasiglia, Edoardo
dc.contributor.authorGhiadoni, Lorenzo
dc.contributor.authorGiannattasio, Cristina
dc.contributor.authorGrassi, Guido
dc.contributor.authorJelakovich, Bojan
dc.contributor.authorJulius, Stevo
dc.contributor.authorMancia, Giuseppe
dc.contributor.authorMcEniery, Carmel
dc.contributor.authorO'Rourke, Michael F
dc.contributor.authorParati, Gianfranco
dc.contributor.authorPauletto, Paolo
dc.contributor.authorPucci, Giacomo
dc.contributor.authorSaladini, Francesca
dc.contributor.authorStrazzullo, Pasquale
dc.contributor.authorTsioufis, Konstantinos
dc.contributor.authorWilkinson, Ian
dc.contributor.authorZanchetti, Alberto
dc.date.accessioned2018-11-22T00:33:02Z
dc.date.available2018-11-22T00:33:02Z
dc.date.issued2018-06
dc.identifier.issn0263-6352
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285684
dc.description.abstract: Whether isolated systolic hypertension in the young (ISHY) implies a worse outcome and needs antihypertensive treatment is still a matter for dispute. ISHY is thought to have different mechanisms than systolic hypertension in the elderly. However, findings from previous studies have provided inconsistent results. From the analysis of the literature, two main lines of research and conceptualization have emerged. Simultaneous assessment of peripheral and central blood pressure led to the identification of a condition called pseudo or spurious hypertension, which was considered an innocent condition. However, an increase in pulse wave velocity has been found by some authors in about 20% of the individuals with ISHY. In addition, obesity and metabolic disturbances have often been documented to be associated with ISHY both in children and young adults. The first aspect to consider whenever evaluating a person with ISHY is the possible presence of white-coat hypertension, which has been frequently found in this condition. In addition, assessment of central blood pressure is useful for identifying ISHY patients whose central blood pressure is normal. ISHY is infrequently mentioned in the guidelines on diagnosis and treatment of hypertension. According to the 2013 European Guidelines on the management of hypertension, people with ISHY should be followed carefully, modifying risk factors by lifestyle changes and avoiding antihypertensive drugs. Only future clinical trials will elucidate if a benefit can be achieved with pharmacological treatment in some subgroups of ISHY patients with associated risk factors and/or high central blood pressure.
dc.format.mediumPrint
dc.languageeng
dc.publisherOvid Technologies (Wolters Kluwer Health)
dc.subjectHumans
dc.subjectHypertension
dc.subjectObesity
dc.subjectAntihypertensive Agents
dc.subjectBlood Pressure Determination
dc.subjectPrognosis
dc.subjectPrevalence
dc.subjectRisk Factors
dc.subjectLife Style
dc.subjectBlood Pressure
dc.subjectAdolescent
dc.subjectAdult
dc.subjectMiddle Aged
dc.subjectChild
dc.subjectSocieties, Medical
dc.subjectEurope
dc.subjectPractice Guidelines as Topic
dc.subjectYoung Adult
dc.subjectWhite Coat Hypertension
dc.subjectPulse Wave Analysis
dc.titleIsolated systolic hypertension in the young: a position paper endorsed by the European Society of Hypertension.
dc.typeArticle
prism.endingPage1236
prism.issueIdentifier6
prism.publicationDate2018
prism.publicationNameJ Hypertens
prism.startingPage1222
prism.volume36
dc.identifier.doi10.17863/CAM.33036
dcterms.dateAccepted2018-02-16
rioxxterms.versionofrecord10.1097/HJH.0000000000001726
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2018-06
dc.contributor.orcidMcEniery, Carmel [0000-0003-3636-0705]
dc.contributor.orcidWilkinson, Ian [0000-0001-6598-9399]
dc.identifier.eissn1473-5598
rioxxterms.typeJournal Article/Review
pubs.funder-project-idBritish Heart Foundation (None)
pubs.funder-project-idBritish Heart Foundation (None)
pubs.funder-project-idBritish Heart Foundation (None)
rioxxterms.freetoread.startdate2019-06-30


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record