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dc.contributor.authorHendy, Jessica
dc.contributor.authorWarinner, Christina
dc.contributor.authorBouwman, Abigail
dc.contributor.authorCollins, Matthew
dc.contributor.authorFiddyment, Sarah
dc.contributor.authorFischer, Roman
dc.contributor.authorHagan, Richard
dc.contributor.authorHofman, Courtney A
dc.contributor.authorHolst, Malin
dc.contributor.authorChaves, Eros
dc.contributor.authorKlaus, Lauren
dc.contributor.authorLarson, Greger
dc.contributor.authorMackie, Meaghan
dc.contributor.authorMcGrath, Krista
dc.contributor.authorMundorff, Amy Z
dc.contributor.authorRadini, Anita
dc.contributor.authorRao, Huiyun
dc.contributor.authorTrachsel, Christian
dc.contributor.authorVelsko, Irina M
dc.contributor.authorSpeller, Camilla F
dc.date.accessioned2018-11-23T00:33:15Z
dc.date.available2018-11-23T00:33:15Z
dc.date.issued2018-07-18
dc.identifier.issn0962-8452
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285851
dc.description.abstractArchaeological dental calculus has emerged as a rich source of ancient biomolecules, including proteins. Previous analyses of proteins extracted from ancient dental calculus revealed the presence of the dietary milk protein β-lactoglobulin, providing direct evidence of dairy consumption in the archaeological record. However, the potential for calculus to preserve other food-related proteins has not yet been systematically explored. Here we analyse shotgun metaproteomic data from 100 archaeological dental calculus samples ranging from the Iron Age to the post-medieval period (eighth century BC to nineteenth century AD) in England, as well as 14 dental calculus samples from contemporary dental patients and recently deceased individuals, to characterize the range and extent of dietary proteins preserved in dental calculus. In addition to milk proteins, we detect proteomic evidence of foodstuffs such as cereals and plant products, as well as the digestive enzyme salivary amylase. We discuss the importance of optimized protein extraction methods, data analysis approaches and authentication strategies in the identification of dietary proteins from archaeological dental calculus. This study demonstrates that proteomic approaches can robustly identify foodstuffs in the archaeological record that are typically under-represented due to their poor macroscopic preservation.
dc.format.mediumElectronic
dc.languageeng
dc.publisherThe Royal Society
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectDental Calculus
dc.subjectProteome
dc.subjectDiet
dc.subjectArchaeology
dc.subjectHistory, Ancient
dc.subjectHistory, Medieval
dc.subjectHistory, 15th Century
dc.subjectHistory, 16th Century
dc.subjectHistory, 17th Century
dc.subjectHistory, 18th Century
dc.subjectHistory, 19th Century
dc.subjectEngland
dc.subjectDNA, Ancient
dc.titleProteomic evidence of dietary sources in ancient dental calculus.
dc.typeArticle
prism.issueIdentifier1883
prism.publicationDate2018
prism.publicationNameProc Biol Sci
prism.volume285
dc.identifier.doi10.17863/CAM.33195
dcterms.dateAccepted2018-06-25
rioxxterms.versionofrecord10.1098/rspb.2018.0977
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2018-07-18
dc.contributor.orcidHendy, Jessica [0000-0002-3718-1058]
dc.contributor.orcidWarinner, Christina [0000-0002-4528-5877]
dc.contributor.orcidCollins, Matthew [0000-0003-4226-5501]
dc.contributor.orcidFiddyment, Sarah [0000-0002-8991-2318]
dc.contributor.orcidFischer, Roman [0000-0002-9715-5951]
dc.contributor.orcidHofman, Courtney A [0000-0002-6808-3370]
dc.contributor.orcidHolst, Malin [0000-0002-4183-7574]
dc.contributor.orcidLarson, Greger [0000-0002-4092-0392]
dc.contributor.orcidMackie, Meaghan [0000-0003-0763-7592]
dc.contributor.orcidSpeller, Camilla F [0000-0001-7128-9903]
dc.identifier.eissn1471-2954
rioxxterms.typeJournal Article/Review
cam.issuedOnline2018-07-18


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International