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dc.contributor.authorWarinner, Christina
dc.contributor.authorSpeller, Camilla
dc.contributor.authorCollins, Matthew
dc.date.accessioned2018-11-23T00:33:16Z
dc.date.available2018-11-23T00:33:16Z
dc.date.issued2015-01-19
dc.identifier.issn0962-8436
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285852
dc.description.abstractThe field of palaeomicrobiology is dramatically expanding thanks to recent advances in high-throughput biomolecular sequencing, which allows unprecedented access to the evolutionary history and ecology of human-associated and environmental microbes. Recently, human dental calculus has been shown to be an abundant, nearly ubiquitous, and long-term reservoir of the ancient oral microbiome, preserving not only microbial and host biomolecules but also dietary and environmental debris. Modern investigations of native human microbiota have demonstrated that the human microbiome plays a central role in health and chronic disease, raising questions about changes in microbial ecology, diversity and function through time. This paper explores the current state of ancient oral microbiome research and discusses successful applications, methodological challenges and future possibilities in elucidating the intimate evolutionary relationship between humans and their microbes.
dc.format.mediumPrint
dc.languageeng
dc.publisherThe Royal Society
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectDental Calculus
dc.subjectHumans
dc.subjectMicrobiological Techniques
dc.subjectArchaeology
dc.subjectFossils
dc.subjectPaleodontology
dc.subjectHigh-Throughput Nucleotide Sequencing
dc.subjectMicrobiota
dc.titleA new era in palaeomicrobiology: prospects for ancient dental calculus as a long-term record of the human oral microbiome.
dc.typeArticle
prism.issueIdentifier1660
prism.publicationDate2015
prism.publicationNamePhilos Trans R Soc Lond B Biol Sci
prism.startingPage20130376
prism.volume370
dc.identifier.doi10.17863/CAM.33196
rioxxterms.versionofrecord10.1098/rstb.2013.0376
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2015-01
dc.contributor.orcidWarinner, Christina [0000-0002-4528-5877]
dc.contributor.orcidSpeller, Camilla [0000-0001-7128-9903]
dc.contributor.orcidCollins, Matthew [0000-0003-4226-5501]
dc.identifier.eissn1471-2970
rioxxterms.typeJournal Article/Review
cam.issuedOnline2015-01-19


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International