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dc.contributor.authorLyne, Anne-Marie
dc.contributor.authorKent, David G
dc.contributor.authorLaurenti, Elisa
dc.contributor.authorCornils, Kerstin
dc.contributor.authorGlauche, Ingmar
dc.contributor.authorPerié, Leïla
dc.date.accessioned2018-12-18T00:31:33Z
dc.date.available2018-12-18T00:31:33Z
dc.date.issued2018-12
dc.identifier.issn0301-472X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/287061
dc.description.abstractInternational experts from multiple disciplines gathered at Homerton College in Cambridge, UK from September 12-14, 2018 to consider recent advances and emerging opportunities in the clonal tracking of hematopoiesis in one of a series of StemCellMathLab workshops. The group included 35 participants with experience in the fields of theoretical and experimental aspects of clonal tracking, and ranged from doctoral students to senior professors. Data from a variety of model systems and from clinical gene therapy trials were discussed, along with strategies for data analysis and sharing and challenges arising due to underlying assumptions in data interpretation and communication. Recognizing the power of this technology underpinned a group consensus of a need for improved mechanisms for sharing data and analytical protocols to maintain reproducibility and rigor in its application to complex tissues.
dc.description.sponsorshipWe thank the BBSRC (BB/R021465/1), the German Stem Cell Network, the Wellcome-MRC Cambridge Stem Cell Institute and the Labex CelTisPhyBio (No. ANR-10-LBX-0038) for funds to support this workshop and the conference staff at Homerton College
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherElsevier BV
dc.subjectClone Cells
dc.subjectStem Cells
dc.subjectDNA Transposable Elements
dc.subjectGenetic Markers
dc.subjectCell Separation
dc.subjectReproducibility of Results
dc.subjectData Display
dc.subjectVirus Integration
dc.subjectHematopoiesis
dc.subjectCell Lineage
dc.subjectMosaicism
dc.subjectModels, Biological
dc.subjectResearch Design
dc.subjectForecasting
dc.subjectClinical Trials as Topic
dc.subjectGuidelines as Topic
dc.subjectDNA Barcoding, Taxonomic
dc.subjectCell Tracking
dc.subjectGenetic Therapy
dc.titleA track of the clones: new developments in cellular barcoding.
dc.typeArticle
prism.endingPage20
prism.publicationDate2018
prism.publicationNameExp Hematol
prism.startingPage15
prism.volume68
dc.identifier.doi10.17863/CAM.34371
dcterms.dateAccepted2018-11-13
rioxxterms.versionofrecord10.1016/j.exphem.2018.11.005
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2018-12
dc.contributor.orcidKent, David [0000-0001-7871-8811]
dc.contributor.orcidLaurenti, Elisa [0000-0002-9917-9092]
dc.identifier.eissn1873-2399
rioxxterms.typeJournal Article/Review
pubs.funder-project-idBiotechnology and Biological Sciences Research Council (BB/R021465/1)
pubs.funder-project-idMedical Research Council (MC_PC_12009)
pubs.funder-project-idEuropean Research Council (715371)
cam.issuedOnline2018-11-15
rioxxterms.freetoread.startdate2019-11-15


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