Patterns of microchromosome organization remain highly conserved throughout avian evolution.
Larkin, Denis M
Griffin, Darren K
Springer Science and Business Media LLC
MetadataShow full item record
O'Connor, R. E., Kiazim, L., Skinner, B., Fonseka, G., Joseph, S., Jennings, R., Larkin, D. M., & et al. (2019). Patterns of microchromosome organization remain highly conserved throughout avian evolution.. Chromosoma, 128 (1), 21-29. https://doi.org/10.1007/s00412-018-0685-6
The structure and organization of a species genome at a karyotypic level, and in interphase nuclei, have broad functional significance. Although regular sized chromosomes are studied extensively in this regard, microchromosomes, which are present in many terrestrial vertebrates, remain poorly explored. Birds have more cytologically indistinguishable microchromosomes (~ 30 pairs) than other vertebrates; however, the degree to which genome organization patterns at a karyotypic and interphase level differ between species is unknown. In species where microchromosomes have fused to other chromosomes, they retain genomic features such as gene density and GC content; however, the extent to which they retain a central nuclear position has not been investigated. In studying 22 avian species from 10 orders, we established that, other than in species where microchromosomal fusion is obvious (Falconiformes and Psittaciformes), there was no evidence of microchromosomal rearrangement, suggesting an evolutionarily stable avian genome (karyotypic) organization. Moreover, in species where microchromosomal fusion has occurred, they retain a central nuclear location, suggesting that the nuclear position of microchromosomes is a function of their genomic features rather than their physical size.
Avian, Conservation, Evolution, Genome, Microchromosome, Animals, Biological Evolution, Birds, Chromosome Painting, Chromosomes, Genome, Karyotyping, Phylogeny, Recombination, Genetic, Species Specificity, Synteny
Biotechnology and Biological Sciences Research Council (BB/N000129/1)
External DOI: https://doi.org/10.1007/s00412-018-0685-6
This record's URL: https://www.repository.cam.ac.uk/handle/1810/287081
Attribution 4.0 International
Licence URL: https://creativecommons.org/licenses/by/4.0/
Recommended or similar items
The current recommendation prototype on the Apollo Repository will be turned off on 03 February 2023. Although the pilot has been fruitful for both parties, the service provider IKVA is focusing on horizon scanning products and so the recommender service can no longer be supported. We recognise the importance of recommender services in supporting research discovery and are evaluating offerings from other service providers. If you would like to offer feedback on this decision please contact us on: email@example.com