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Assaying reproductive capacity in female rodents

Accepted version
Peer-reviewed

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Type

Book chapter

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Authors

Aiken, CEM 
Tarry-Adkins, Jane 

Abstract

It is an important part of many rodent studies to assess reproductive capacity in the female. Animal models that involve exposure to organic compounds, teratogenicity studies, or exposure to suboptimal environments during early development often result in deficits in female fertility. In addition to longitudinal physiology assays of fecundity, there are several molecular biology approaches to assessing female reproductive potential that can be performed to provide a ‘snap-shot’ of fertility potential at a single time-point. Here we describe some of the most useful ways to assess female reproductive capacity in rodents.

Description

Title

Assaying reproductive capacity in female rodents

Keywords

Estropause, Female, Follicle, Ovary, Reproductive system, Animals, Female, Fertility, Humans, Models, Animal, Reproduction, Rodentia

Is Part Of

Pre-Clinical Models. Methods in Molecular Biology

Book type

Publisher

Humana Press

ISBN

978-1-4939-8993-5
Sponsorship
Addenbrooke's Charitable Trust (ACT) (13/17 B (iii))
MRC (MC_UU_00014/4)