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Supercontinuum radiation in fluorescence microscopy and biomedical imaging applications

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Kaminski, Clemens F 

Abstract

Compact, high brightness supercontinuum sources have already made a big impact in the fields of fluorescence microscopy and other biomedical imaging techniques, such as optical coherence tomography and coherent anti-Stokes Raman scattering. In this review, we provide a brief overview on the generation and properties of supercontinuum radiation for imaging applications. We review specific uses of supercontinuum sources and their potential for imaging, but also their limitations and caveats. We conclude with a review of recent advances in UV supercontinuum generation, near-IR microscopy, exciting new potentials for the use of hollow-core PCFs, on-chip supercontinuum generation, and technologies to improve supercontinuum stability for certain applications.

Description

Keywords

5108 Quantum Physics, 40 Engineering, 4008 Electrical Engineering, 51 Physical Sciences, 5102 Atomic, Molecular and Optical Physics

Journal Title

Journal of the Optical Society of America B: Optical Physics

Conference Name

Journal ISSN

0740-3224
1520-8540

Volume Title

36

Publisher

Optical Society of America
Sponsorship
European Commission Horizon 2020 (H2020) Marie Sk?odowska-Curie actions (722380)
Engineering and Physical Sciences Research Council (EP/L015889/1)
Wellcome Trust (089703/Z/09/Z)
Biotechnology and Biological Sciences Research Council (BB/H023917/1)
Engineering and Physical Sciences Research Council (EP/H018301/1)
Medical Research Council (MR/K015850/1)
Medical Research Council (MR/K02292X/1)
H2020 Marie Skłodowska-Curie Actions (MSCA) (722380); MedImmune; Infinitus (China) Ltd.; Engineering and Physical Sciences Research Council (EPSRC) (EP/H018301/1, EP/L015889/1); Wellcome Trust (089703/Z/09/Z, 3-3249/Z/16/Z); Medical Research Council (MRC) (MR/K015850/1, MR/K02292X/1).