Axial acoustic field barrier for fluidic particle manipulation
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Authors
Li, N
Kale, Akshay
Stevenson, Adrian
Publication Date
2019-01-07Journal Title
Applied Physics Letters
ISSN
0003-6951
Publisher
American Institute of Physics
Volume
114
Issue
1
Type
Article
This Version
AM
Metadata
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Li, N., Kale, A., & Stevenson, A. (2019). Axial acoustic field barrier for fluidic particle manipulation. Applied Physics Letters, 114 (1)https://doi.org/10.1063/1.5052009
Abstract
An acoustic field barrier integrated within a flow tubing system to achieve high-throughput separation of particles in fluid is reported in this work. We investigate the axial acoustic field of a piezo-tube with an inside diameter of 34 mm, a length of 25 mm, and an operating frequency of 1.15 MHz. Energy concentrates within the tube, and leakage at the ends provides a sharp monotonic acoustic pressure field within a fluidic circuit. This process is not the conventional standing wave mechanism; instead, the geometry produces a spatially stable filtering action without fouling. This powerful filtering action is confirmed theoretically via a COMSOL simulation and demonstrated experimentally by concentrating suspensions of 5 μm proteoglycan tracer particles at a flow rate of 20 ml/min: The corresponding acoustic contrast factor is 0.243, and the trapping force is 11pN. This tube geometry tackles the limitations of microfluidic standing wave based acoustic concentrators, namely, complex extraction, low-throughput, and distributed focus, by harnessing a stable monotonic field profile.
Sponsorship
BBSRC (1175)
Innovate UK (102795)
Identifiers
External DOI: https://doi.org/10.1063/1.5052009
This record's URL: https://www.repository.cam.ac.uk/handle/1810/289004
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