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dc.contributor.authorLi, Nen
dc.contributor.authorKale, Akshayen
dc.contributor.authorStevenson, Adrianen
dc.date.accessioned2019-02-08T00:33:23Z
dc.date.available2019-02-08T00:33:23Z
dc.date.issued2019-01-07en
dc.identifier.issn0003-6951
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/289004
dc.description.abstractAn acoustic field barrier integrated within a flow tubing system to achieve high-throughput separation of particles in fluid is reported in this work. We investigate the axial acoustic field of a piezo-tube with an inside diameter of 34 mm, a length of 25 mm, and an operating frequency of 1.15 MHz. Energy concentrates within the tube, and leakage at the ends provides a sharp monotonic acoustic pressure field within a fluidic circuit. This process is not the conventional standing wave mechanism; instead, the geometry produces a spatially stable filtering action without fouling. This powerful filtering action is confirmed theoretically via a COMSOL simulation and demonstrated experimentally by concentrating suspensions of 5 μm proteoglycan tracer particles at a flow rate of 20 ml/min: The corresponding acoustic contrast factor is 0.243, and the trapping force is 11pN. This tube geometry tackles the limitations of microfluidic standing wave based acoustic concentrators, namely, complex extraction, low-throughput, and distributed focus, by harnessing a stable monotonic field profile.
dc.publisherAmerican Institute of Physics
dc.titleAxial acoustic field barrier for fluidic particle manipulationen
dc.typeArticle
prism.issueIdentifier1en
prism.publicationDate2019en
prism.publicationNameApplied Physics Lettersen
prism.volume114en
dc.identifier.doi10.17863/CAM.36267
dcterms.dateAccepted2018-12-31en
rioxxterms.versionofrecord10.1063/1.5052009en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2019-01-07en
dc.identifier.eissn1077-3118
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idBBSRC (1175)
pubs.funder-project-idInnovate UK (102795)
rioxxterms.freetoread.startdate2020-01-07


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