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Towards Closed-Loop Integration of Point-of-Care Technologies.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Tan, Edward KW 
Au, Yan Zi 
Moghaddam, Gita Khalili 
Occhipinti, Luigi G 
Lowe, Christopher R 

Abstract

Point-of-care (PoC) diagnostics promises to yield test results accessible anytime and anywhere. Its application has expanded from providing healthcare necessities to the real-time monitoring of the ageing and health conscious population. Following the evolving consumer demand, there is a trend toward developing non- and minimally invasive PoC tests. Emerging PoC sensors have not only demonstrated multifunctional capabilities such as sweat stimulation but also can be connected to drug delivery units via a wireless network, enabling an active role of the technology in disease management. This review article summarises the latest developments in non- and minimally invasive PoC diagnostics and provides an overview on the progress towards closed-loop integration of complementary technologies for comprehensive and autonomous patient care.

Description

Keywords

autonomous, closed loop, diagnostics, minimally invasive, non-invasive, point of care

Journal Title

Trends Biotechnol

Conference Name

Journal ISSN

0167-7799
1879-3096

Volume Title

Publisher

Elsevier BV
Sponsorship
Engineering and Physical Sciences Research Council (EP/K03099X/1)
E.K.W.T. received funding from Trinity Hall, University of Cambridge and the IET Postgraduate Scholarship. Y.Z.A. received funding from Wellcome Trust.