Current Management of Intracranial Germ Cell Tumours.
Bowzyk Al-Naeeb, A
Clinical oncology (Royal College of Radiologists (Great Britain))
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Bowzyk Al-Naeeb, A., Murray, M., Horan, G., Harris, F., Kortmann, R., Nicholson, J., & Ajithkumar, T. (2018). Current Management of Intracranial Germ Cell Tumours.. Clinical oncology (Royal College of Radiologists (Great Britain)), 30 (4), 204-214. https://doi.org/10.1016/j.clon.2018.01.009
© 2018 The Royal College of Radiologists Intracranial germ cell tumours (icGCTs) are uncommon tumours occurring in children and young adults. They are usually segregated into germinomas and non-germinomatous tumours (NGGCTs) in most classifications. Germinomas are highly curable tumours with multimodality treatment, but NGGCTs are associated with poorer survival outcomes. There are some differences in the approach to the management of icGCTs globally. Current research generally focuses on reducing treatment intensity, particularly the dose and volume of radiotherapy, in order to minimise the risks of late sequelae while maintaining high cure rates in icGCTs.
Humans, Neoplasms, Germ Cell and Embryonal, Brain Neoplasms, Disease Progression, Combined Modality Therapy, Adolescent, Child, Female, Male, Young Adult
External DOI: https://doi.org/10.1016/j.clon.2018.01.009
This record's URL: https://www.repository.cam.ac.uk/handle/1810/289476