Did Going North Give Us Migraine? An Evolutionary Approach on Understanding Latitudinal Differences in Migraine Epidemiology.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Viganò, Alessandro
Manica, Andrea
Di Piero, Vittorio
Leonardi, Michela https://orcid.org/0000-0001-8933-9374
Abstract
This commentary discusses a recent publication by evolutionary biologists with strong implications for migraine experts. The Authors showed that a gene polymorphism associated with migraine gave our ancestors an evolutionary advantage when colonizing northern, and thus colder, territories. They then highlight that the prevalence of migraine may differ among countries because of climatic adaptation. These results may prove useful in planning both epidemiological and physiological studies in the field of migraine.
Description
Keywords
TRPM8, cold adaptation, evolutionary biology, latitude, migraine, migraine epidemiology, Biological Evolution, Climate, Geography, Humans, Migraine Disorders, Polymorphism, Single Nucleotide, TRPM Cation Channels
Journal Title
Headache
Conference Name
Journal ISSN
0017-8748
1526-4610
1526-4610
Volume Title
59
Publisher
Wiley
Publisher DOI
Sponsorship
European Research Council (647787)