Under Pressure: When a Transformed Environment Pushes Cells to Malignancy.
Cell Stem Cell
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García-Fernández, M., & Mendez-Ferrer, S. (2016). Under Pressure: When a Transformed Environment Pushes Cells to Malignancy.. Cell Stem Cell, 19 (5), 559-560. https://doi.org/10.1016/j.stem.2016.10.012
Mesenchymal stem/progenitor cells (MSPCs) have recently gained attention as key elements that contribute to different stages of oncogenesis, from predisposition to disease manifestation and evolution. In this issue of Cell Stem Cell, Zambetti et al. (2016) propose a mechanism by which mutated MSPCs transform hematopoietic cells into a malignant-prone state.
Medical Research Council (MC_PC_12009), European Research Council (648765)
ECH2020 EUROPEAN RESEARCH COUNCIL (ERC) (648765)
External DOI: https://doi.org/10.1016/j.stem.2016.10.012
This record's URL: https://www.repository.cam.ac.uk/handle/1810/292115