Looking back on the alternative complement pathway.

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Authors
  Lachmann, Sir Peter
Publication Date
2018-08
Journal Title
Immunobiology
ISSN
0171-2985
Publisher
Elsevier
Volume
223
Issue
8-9
Pages
519-523
Language
eng
Type
Article
This Version
AM
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Citation
Lachmann, S. P. (2018). Looking back on the alternative complement pathway.. Immunobiology, 223 (8-9), 519-523. https://doi.org/10.1016/j.imbio.2018.02.001
Abstract
The alternative pathway of complement originated from the Properdin pathway originally described by the Pillemer laboratory in the 1950s. This work generated great controversy and it took several decades for a consensus on its components, its reaction sequence and its functions to emerge. This paper reviews this history and attempts to clarify some of the ambiguities that remain.
Keywords
Alternative pathway, Complement, Properdin, Animals, Complement Pathway, Alternative, History, 20th Century, History, 21st Century, Humans, Properdin
Identifiers
External DOI: https://doi.org/10.1016/j.imbio.2018.02.001
This record's URL: https://www.repository.cam.ac.uk/handle/1810/292129
Rights
Licence:
http://creativecommons.org/licenses/by-nc-nd/4.0/
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