Organic Electronics for Point-of-Care Metabolite Monitoring.
Trends in Biotechnology
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Pappa, A., Parlak, O., Scheiblin, G., Mailley, P., Salleo, A., & Owens, R. (2018). Organic Electronics for Point-of-Care Metabolite Monitoring.. Trends in Biotechnology, 36 (1), 45-59. https://doi.org/10.1016/j.tibtech.2017.10.022
In this review we focus on demonstrating how organic electronic materials can solve key problems in biosensing thanks to their unique material properties and implementation in innovative device configurations. We highlight specific examples where these materials solve multiple issues related to complex sensing environments, and we benchmark these examples by comparing them to state-of-the-art commercially available sensing using alternative technologies. We have categorized our examples by sample type, focusing on sensing from body fluids in vitro and on wearable sensors, which have attracted significant interest owing to their integration with everyday life activities. We finish by describing a future trend for in vivo, implantable sensors, which aims to build on current progress from sensing in biological fluids ex vivo.
biosensors, diagnostics, metabolites, organic electronics, point-of-care, wearable, Biosensing Techniques, Diagnostic Tests, Routine, Electronics, Humans, Metabolomics, Point-of-Care Systems
A.M.P and R.O. gratefully acknowledge the support by the Marie Curie Innovative Training Network (ITN) project OrgBio 607896. O.P. gratefully acknowledges support from the Knut and Alice Wallenberg Foundation (KAW 2014.0387) for postdoctoral research at Stanford University.
External DOI: https://doi.org/10.1016/j.tibtech.2017.10.022
This record's URL: https://www.repository.cam.ac.uk/handle/1810/292167