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Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Taylor-Brown, Frances E 
Greville-Heygate, Oliver 
Constantino-Casas, Fernando 
Williams, David L 

Abstract

An 8-year-old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma.

Description

Keywords

brain neoplasia, calvarium, skull defect, Animals, Carcinoma, Choroid Plexus Neoplasms, Dog Diseases, Dogs, Magnetic Resonance Imaging, Male, Multimodal Imaging, Skull, Ultrasonography

Journal Title

Vet Radiol Ultrasound

Conference Name

Journal ISSN

1058-8183
1740-8261

Volume Title

62

Publisher

Wiley

Rights

All rights reserved