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A Machine Learning Tool for Interpreting Differences in Cognition Using Brain Features

Accepted version
Peer-reviewed

Type

Conference Object

Change log

Authors

Lió, P 
Toschi, N 

Abstract

Predicting variability in cognition traits is an attractive and challenging area of research, where different approaches and datasets have been implemented with mixed results. Some powerful Machine Learning algorithms employed before are difficult to interpret, while other algorithms are easy to interpret but might not be as powerful. To improve understanding of individual cognitive differences in humans, we make use of the most recent developments in Machine Learning in which powerful prediction models can be interpreted with confidence. We used neuroimaging data and a variety of behavioural, cognitive, affective and health measures from 905 people obtained from the Human Connectome Project (HCP). As a main contribution of this paper, we show how one could interpret the neuroanatomical basis of cognition, with recent methods which we believe are not yet fully explored in the field. By reducing neuroimages to a well characterised set of features generated from surface-based morphometry and cortical myelin estimates, we make the interpretation of such models easier as each feature is self-explanatory. The code used in this tool is available in a public repository: https://github.com/tjiagoM/interpreting-cognition-paper-2019.

Description

Keywords

46 Information and Computing Sciences, Basic Behavioral and Social Science, Bioengineering, Behavioral and Social Science, Neurological, Mental health, 3 Good Health and Well Being

Journal Title

IFIP Advances in Information and Communication Technology

Conference Name

15th International Conference on Artificial Intelligence Applications and Innovations

Journal ISSN

1868-4238
1868-422X

Volume Title

559

Publisher

Springer International Publishing

Rights

All rights reserved
Sponsorship
Cambridge University Hospitals NHS Foundation Trust (CUH) (unknown)
Medical Research Council (MR/P01271X/1)