Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity.

Brandhorst, T Tristan; Kean, Iain; Lawry, Stephanie M; Wiesner, Darin L; Klein, Bruce S

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Authors

Brandhorst, T Tristan

Kean, Iain

Lawry, Stephanie M

Wiesner, Darin L

Klein, Bruce S

Publication Date

2019-03-25

Journal Title

Scientific reports

ISSN

2045-2322

Volume

Issue

Pages

5047

Language

eng

Type

Article

This Version

VoR

Physical Medium

Electronic

Metadata

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Citation

Brandhorst, T. T., Kean, I., Lawry, S. M., Wiesner, D. L., & Klein, B. S. (2019). Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity.. Scientific reports, 9 (1), 5047. https://doi.org/10.1038/s41598-019-41564-9

Keywords

Saccharomyces cerevisiae, Pyruvaldehyde, Dioxoles, Pyrroles, Triose-Phosphate Isomerase, Saccharomyces cerevisiae Proteins, Amino Acid Substitution, Drug Resistance, Fungal, Mutation, Missense, Stress, Physiological, Histidine Kinase

Identifiers

External DOI: https://doi.org/10.1038/s41598-019-41564-9

This record's URL: https://www.repository.cam.ac.uk/handle/1810/293153

Rights

Attribution 4.0 International

Licence URL: https://creativecommons.org/licenses/by/4.0/

Except where otherwise noted, this item's licence is described as Attribution 4.0 International