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dc.contributor.authorTan, WKen
dc.contributor.authorDi Pietro, Massimilianoen
dc.contributor.authorFitzgerald, Rebeccaen
dc.date.accessioned2017-05-05T17:11:49Z
dc.date.accessioned2019-05-30T13:20:31Z
dc.date.available2017-05-05T17:11:49Z
dc.date.available2019-05-30T13:20:31Z
dc.date.issued2017-02-16en
dc.identifier.issn0748-7983
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/293253
dc.description.abstractBarrett's oesophagus is a condition which predisposes towards development of oesophageal adenocarcinoma, a highly lethal tumour which has been increasing in incidence in the Western world over the past three decades. There have been tremendous advances in the field of Barrett's oesophagus, not only in diagnostic modalities, but also in therapeutic strategies available to treat this premalignant disease. In this review, we discuss the past, present and future of Barrett's oesophagus. We describe the historical and new evolving diagnostic criteria of Barrett's oesophagus, while also comparing and contrasting the British Society of Gastroenterology guidelines, American College of Gastroenterology guidelines and International Benign Barrett's and CAncer Taskforce (BOBCAT) for Barrett's oesophagus. Advances in endoscopic modalities such as confocal and volumetric laser endomicroscopy, and a non-endoscopic sampling device, the Cytosponge, are described which could aid in identification of Barrett's oesophagus. With regards to therapy we review the evidence for the utility of endoscopic mucosal resection and radiofrequency ablation when coupled with better characterization of dysplasia. These endoscopic advances have transformed the management of Barrett's oesophagus from a primarily surgical disease into an endoscopically managed condition.
dc.description.sponsorshipThe BEST-1 study was funded by the Medical Research Council gap fund. The BEST-2 study was funded by Cancer Research UK.
dc.languageengen
dc.language.isoenen
dc.publisherElsevier
dc.relation.replaceshttps://www.repository.cam.ac.uk/handle/1810/264122
dc.relation.replaces1810/264122
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectBarrett's oesophagusen
dc.subjectdiagnosisen
dc.subjectmanagementen
dc.subjectguidelinesen
dc.subjectendoscopyen
dc.subjectcytospongeen
dc.titlePast, present and future of Barrett's oesophagusen
dc.typeArticle
prism.publicationDate2017en
prism.publicationNameEuropean Journal of Surgical Oncologyen
dc.identifier.doi10.17863/CAM.9485
dc.identifier.doi10.17863/CAM.40405
dcterms.dateAccepted2017-02-06en
rioxxterms.versionofrecord10.1016/j.ejso.2017.02.004en
rioxxterms.versionVoRen
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2017-02-16en
dc.contributor.orcidDi Pietro, Massimiliano [0000-0003-4866-7026]
dc.contributor.orcidFitzgerald, Rebecca [0000-0002-3434-3568]
dc.identifier.eissn1532-2157
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idMedical Research Council (MC_UU_12022/2)


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International