© 2014 The Cochrane Collaboration. This is the protocol for a review and there is no abstract. The objectives are as follows: Primary objective To assess the effectiveness of health promotion interventions in community pharmacy practice settings on pharmacy workers and pharmacy clients (including diagnosed patients) when compared to i) No treatment controlsii) Usual treatment controlsiii) Other active intervention Secondary objectives To assess whether there are differences in effectiveness of health promotion interventions in community pharmacy practice settings on i) Pharmacy workerii) Client (patient) with regard to: i) Ethnicity of patientsii) Country income level (World Bank Group 2009)iii) Extent of adverse health behaviour (defined according to national guidelines where available)iv) Type of pharmacy worker delivering the intervention (e.g. pharmacist versus pharmacist technician)v) Theoretical constructs/components and behaviour change techniques employed in the interventionvi) Costs of health care