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dc.contributor.authorTesoro, Salvatoreen
dc.contributor.authorAhnert, Sebastianen
dc.contributor.authorLeonard, Alexanderen
dc.date.accessioned2019-08-01T23:30:30Z
dc.date.available2019-08-01T23:30:30Z
dc.date.issued2018-08en
dc.identifier.issn2470-0045
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/295187
dc.description.abstractSelf-assembly processes are widespread in nature and lie at the heart of many biological and physical phenomena. The characteristics of self-assembly building blocks determine the structures that they form. Two crucial properties are the determinism and boundedness of the self-assembly. The former tells us whether the same set of building blocks always generates the same structure, and the latter whether it grows indefinitely. These properties are highly relevant in the context of protein structures, as the difference between deterministic protein self-assembly and nondeterministic protein aggregation is central to a number of diseases. Here we introduce a graph theoretical approach that can determine the determinism and boundedness for several geometries and dimensionalities of self-assembly more accurately and quickly than conventional methods. We apply this methodology to a previously studied lattice self-assembly model and discuss generalizations to a wide range of other self-assembling systems.
dc.format.mediumPrinten
dc.languageengen
dc.publisherAmerican Physical Society
dc.rightsAll rights reserved
dc.rights.uri
dc.titleDeterminism and boundedness of self-assembling structures.en
dc.typeArticle
prism.issueIdentifier2-1en
prism.publicationDate2018en
prism.publicationNamePhysical review. Een
prism.startingPage022113
prism.volume98en
dc.identifier.doi10.17863/CAM.42249
dcterms.dateAccepted2018-07-27en
rioxxterms.versionofrecord10.1103/physreve.98.022113en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2018-08en
dc.contributor.orcidTesoro, Salvatore [0000-0003-4011-366X]
dc.contributor.orcidLeonard, Alexander [0000-0001-8425-5630]
dc.identifier.eissn2470-0053
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idEPSRC (1805372)


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