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Simultaneous Transients of Intracranial Pressure and Heart Rate in Traumatic Brain Injury: Methods of Analysis.

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Peer-reviewed

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Article

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Authors

Dimitri, Giovanna Maria 
Agrawal, Shruti 
Young, Adam 

Abstract

OBJECTIVES: The detection of increasing intracranial pressure (ICP) is important in preventing secondary brain injuries. Before mean ICP increases critically, transient ICP elevations may be observed. We have observed ICP transients of less than 10 min duration ,which occurred simultaneously with transient increases in heart rate (HR). These simultaneous events in HR and ICP suggest a direct interaction or communication between the heart and the brain. METHODS: This chapter describes four mathematical methods and their applicability in detecting the above heart-brain cross-talk events during long-term monitoring of ICP. RESULTS: Recurrence plots, cross-correlation function and wavelet analysis confirmed the relationship between ICP and HR time series. Using the peaks detection algorithm with a sliding window approach we found an average of 37 cross-talk events (± SD 39). The number of events detected varied among patients, from 1 to more than 150 events. CONCLUSION: Our analysis suggested that the peaks detection algorithm based on a sliding window approach is feasible for detecting simultaneous peaks, e.g. cross-talk events in the ICP and HR signals.

Description

Keywords

Cross-talk, Heart rate, Intracranial pressure, Peaks detection, Recurrence plots, Wavelet analysis, Algorithms, Arterial Pressure, Brain Injuries, Traumatic, Child, Female, Heart Rate, Humans, Intracranial Hypertension, Intracranial Pressure, Male, Monitoring, Physiologic, Wavelet Analysis

Journal Title

Acta Neurochirurgica: Supplementum

Conference Name

Journal ISSN

0065-1419
2197-8395

Volume Title

126

Publisher

Springer Nature

Rights

All rights reserved
Sponsorship
Medical Research Council (G0600986)
EPSRC (1649557)
Medical Research Council (G0600986/1)