Role of the general practitioner in the care of BRCA1 and BRCA2 mutation carriers: General practitioner and patient perspectives.
Vande Perre, Pierre
Molecular Genetics & Genomic Medicine
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Vande Perre, P., Toledano, D., Corsini, C., Escriba, E., Laporte, M., Bertet, H., Yauy, K., et al. (2018). Role of the general practitioner in the care of BRCA1 and BRCA2 mutation carriers: General practitioner and patient perspectives.. Molecular Genetics & Genomic Medicine, 6 (6), 957-965. https://doi.org/10.1002/mgg3.464
BACKGROUND: General practitioners (GPs) have an increasing role in referring patients with putative mutation in BRCA1/2 genes for genetics consultation and for long-term follow-up of mutation carriers. METHODS: We compared the expectations of the GPs' role according to BRCA1/2 mutation carriers and to GPs themselves. RESULTS: Overall, 38% (58/152) of eligible GPs and 70% (176/252) of eligible patients were surveyed. Although 81% of GPs collected the family history, only 24% considered that they know criteria indicating genetics consultation and 39% sufficient knowledge of BRCA1/2 guidelines to answer patients' questions. Twelve% of GPs were aware of the French national guidelines. Among unsatisfied patients, 40% felt that their GP was able to answer (moderately, sufficiently, or completely) specific questions about BRCA1/2 care as compared with 81% in satisfied patients. Only 33% of GPs reported being informed directly by the geneticist about the patients' results. GPs' main expectations for their role in BRCA1/2 carrier care were psychological support and informing relatives about screening (72% and 71%, respectively), which contrasts with the perceptions of patients, who mainly requested medical advice for BRCA1/2-related care (51%). CONCLUSION: There is an important need for GP training and enhancing interactions between GPs and geneticists to improve the GP's role in BRCA1/2 screening and management.
BRCA1, BRCA2, general practitioners, genetic screening, hereditary breast and ovarian cancer syndrome, Adult, Aged, Aged, 80 and over, BRCA1 Protein, BRCA2 Protein, Breast Neoplasms, Female, General Practitioners, Genetic Carrier Screening, Genetic Counseling, Health Knowledge, Attitudes, Practice, Humans, Middle Aged, Referral and Consultation
This work was supported by Montpellier University Hospital and the association “Les Sapins de Noel des Créateurs de Paris et du Luxembourg.”
Cancer Research UK (16561)
External DOI: https://doi.org/10.1002/mgg3.464
This record's URL: https://www.repository.cam.ac.uk/handle/1810/297135
Attribution 4.0 International
Licence URL: https://creativecommons.org/licenses/by/4.0/