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dc.contributor.authorPassamonti, Lucaen
dc.contributor.authorRiccelli, Ren
dc.contributor.authorIndovina, Ien
dc.contributor.authorDuggento, Aen
dc.contributor.authorTerracciano, Aen
dc.contributor.authorToschi, Nen
dc.date.accessioned2019-10-03T23:30:44Z
dc.date.available2019-10-03T23:30:44Z
dc.date.issued2019-10-21en
dc.identifier.issn2045-2322
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/297436
dc.description.abstractThe human brain is characterized by highly dynamic patterns of functional connectivity. However, it is unknown whether this time-variant ‘connectome’ is related to individual differences in the personality traits described in the five-factor model. To answer this question, inter-network time-variant (non-stationarity) connectivity was computed in n=818 healthy people via a dynamical conditional correlation model. Next, network dynamicity was quantified throughout an ad-hoc measures (T-index) and the generalizability of the multi-variate associations between personality traits and network dynamicity was assessed using a train/test split approach. Conscientiousness, reflecting enhanced cognitive and emotional control, was the sole personality trait linked to stationary connectivity across several circuits such as the default mode and prefronto-parietal networks. The stationarity in the ‘communication’ across large-scale networks offers a mechanistic explanation of the capacity of conscientious people to ‘protect’ non-immediate goals against interference over-time. This study informs future research aiming at developing more realistic models of the brain dynamics mediating personality differences.
dc.format.mediumElectronicen
dc.languageengen
dc.publisherNature Publishing Group
dc.rightsAll rights reserved
dc.rights.uri
dc.subjectNerve Neten
dc.subjectHumansen
dc.subjectMagnetic Resonance Imagingen
dc.subjectPersonalityen
dc.subjectModels, Biologicalen
dc.subjectTime Factorsen
dc.subjectImage Processing, Computer-Assisteden
dc.subjectAdulten
dc.subjectFemaleen
dc.subjectMaleen
dc.subjectYoung Adulten
dc.subjectConnectomeen
dc.subjectSurveys and Questionnairesen
dc.titleTime-resolved connectome of the five-factor model of personality.en
dc.typeArticle
prism.issueIdentifier1en
prism.publicationDate2019en
prism.publicationNameScientific reportsen
prism.startingPage15066
prism.volume9en
dc.identifier.doi10.17863/CAM.44497
dcterms.dateAccepted2019-10-02en
rioxxterms.versionofrecord10.1038/s41598-019-51469-2en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2019-10-21en
dc.contributor.orcidPassamonti, Luca [0000-0002-7937-0615]
dc.contributor.orcidIndovina, I [0000-0002-1183-0013]
dc.contributor.orcidDuggento, A [0000-0001-6030-5269]
dc.contributor.orcidTerracciano, A [0000-0001-5799-8885]
dc.contributor.orcidToschi, N [0000-0003-1929-5833]
dc.identifier.eissn2045-2322
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idMRC (MR/P01271X/1)
cam.orpheus.successMon Jun 08 08:22:07 BST 2020 - The item has an open VoR version.*
rioxxterms.freetoread.startdate2022-10-03


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