Changes in Cognitive Impairment in the Czech Republic.
Authors
Seblova, Dominika
Machů, Vendula
Kuklová, Marie
Kopecek, Miloslav
Cermakova, Pavla
Publication Date
2019Journal Title
J Alzheimers Dis
ISSN
1387-2877
Publisher
IOS Press
Volume
72
Issue
3
Pages
693-701
Language
eng
Type
Article
This Version
AM
Physical Medium
Print
Metadata
Show full item recordCitation
Seblova, D., Brayne, C., Machů, V., Kuklová, M., Kopecek, M., & Cermakova, P. (2019). Changes in Cognitive Impairment in the Czech Republic.. J Alzheimers Dis, 72 (3), 693-701. https://doi.org/10.3233/JAD-190688
Abstract
BACKGROUND: Studies from North America and Western Europe suggest stable or declining trends in impaired cognition across birth cohorts. OBJECTIVE: We aimed to examine changes in the age-specific prevalence of cognitive impairment in the Czech Republic. METHODS: The study used two samples from the population-based Czech Survey on Health, Ageing and Retirement in Europe. Age-specific prevalence of cognitive impairment (defined based on scores in verbal fluency, immediate recall, delayed recall, and temporal orientation) was compared between participants in wave 2 (2006/2007; n = 1,107) and wave 6 (2015; n = 3,104). Logistic regression was used to estimate the association between the wave and cognitive impairment, step-wise adjusting for sociodemographic and clinical characteristics. Multiple sensitivity analyses, focusing on alternative operationalizations of relative cognitive impairment, impact of missing cognitive data, and survival bias, were carried out. RESULTS: The most conservative estimate suggested that the age-specific prevalence of cognitive impairment declined by one fifth, from 11% in 2006/2007 to 9% in 2015. Decline was observed in all sensitivity analyses. The change was associated with differences in physical inactivity, management of high blood cholesterol, and increases in length education. CONCLUSION: Older adults in the Czech Republic, a country situated in the Central and Eastern European region, have achieved positive developments in cognitive aging. Longer education, better management of cardiovascular factors, and reduced physical inactivity seem to be of key importance.
Keywords
Humans, Health Surveys, Longitudinal Studies, Prospective Studies, Aging, Aged, Aged, 80 and over, Czech Republic, Female, Male, Independent Living, Cognitive Dysfunction
Sponsorship
The present study was supported by Czech Alzheimer Foundation.
Identifiers
External DOI: https://doi.org/10.3233/JAD-190688
This record's URL: https://www.repository.cam.ac.uk/handle/1810/297490
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