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dc.contributor.authorPaterson, Ianen
dc.contributor.authorLam, Nelsonen
dc.date.accessioned2019-10-30T00:30:28Z
dc.date.available2019-10-30T00:30:28Z
dc.date.issued2019-10-18
dc.identifier.issn1434-193X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/298190
dc.description.abstractMarine polyketide natural products represent a fertile area of chemical space for the continual discovery of promising drug candidates. Advancements in spectroscopic and computational techniques have allowed for the increasingly facile structural and stereochemical determination of these biologically active molecules. However, their inherent architectural complexity often precludes a complete assignment even by the most discerning isolation chemists. This Minireview highlights how carefully conceived synthetic plans, employing highly stereocontrolled reactions, have enabled the configurational assignment of several polyketide natural products.
dc.relation.isreplacedby1810/298675
dc.relation.isreplacedbyhttps://www.repository.cam.ac.uk/handle/1810/298675
dc.rightsAll rights reserved
dc.rights.uri
dc.subjectAldol reaction • Polyketide • Total Synthesis • Natural Products • Stereocontrolen
dc.titleStereocontrolled synthesis as an enabling tool for the configurational assignment of marine polyketide natural productsen
dc.typeArticle
dc.identifier.doi10.17863/CAM.44554
pubs.declined2019-10-05T14:47:29.216+0100
pubs.deleted2019-10-05T14:47:29.216+0100
pubs.merge-to1810/298675
pubs.merge-tohttps://www.repository.cam.ac.uk/handle/1810/298675
rioxxterms.versionofrecord10.1002/ejoc.201901243
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
dc.contributor.orcidLam, Nelson [0000-0002-9307-0619]
rioxxterms.typeJournal Article/Reviewen
cam.orpheus.successTue Jul 28 15:41:57 BST 2020 - Embargo updated*
cam.orpheus.counter20*
rioxxterms.freetoread.startdate2020-10-18


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