Molecular interactome between HSCs and their niches.
American Society of Hematology
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Méndez-Ferrer, S. (2019). Molecular interactome between HSCs and their niches.. Blood, 134 (15), 1197-1198. https://doi.org/10.1182/blood.2019002615
Because hematopoietic stem cells (HSCs) were found to require a bone marrow (BM) habitat for long-term function, many studies have attempted to dissect key cellular and molecular interactions between HSCs and their BM microenvironments or HSC niches. In this issue of Blood, Mende et al provide a computational method to infer potential ligand-receptor interactions between murine hematopoietic stem and progenitor cells (HSPCs) and their niche-forming cells.
Bone Marrow Cells, Stem Cell Niche
European Research Council (648765)
NHS Blood and Transplant (NHSBT)
European Commission Horizon 2020 (H2020) Marie Sk?odowska-Curie actions (708411)
Cancer Research UK (C61367/A26670)
Medical Research Council (MC_PC_12009)
External DOI: https://doi.org/10.1182/blood.2019002615
This record's URL: https://www.repository.cam.ac.uk/handle/1810/298987
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