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Molecular interactome between HSCs and their niches.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Méndez-Ferrer, Simón  ORCID logo  https://orcid.org/0000-0002-9805-9988

Abstract

Because hematopoietic stem cells (HSCs) were found to require a bone marrow (BM) habitat for long-term function, many studies have attempted to dissect key cellular and molecular interactions between HSCs and their BM microenvironments or HSC niches. In this issue of Blood, Mende et al provide a computational method to infer potential ligand-receptor interactions between murine hematopoietic stem and progenitor cells (HSPCs) and their niche-forming cells.

Description

Keywords

Bone Marrow Cells, Stem Cell Niche

Journal Title

Blood

Conference Name

Journal ISSN

0006-4971
1528-0020

Volume Title

134

Publisher

American Society of Hematology

Rights

All rights reserved
Sponsorship
European Research Council (648765)
NHS Blood and Transplant (NHSBT)
European Commission Horizon 2020 (H2020) Marie Sk?odowska-Curie actions (708411)
Cancer Research UK (C61367/A26670)
Medical Research Council (MC_PC_12009)