Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.

Loreto, Andrea; Hill, Ciaran S; Hewitt, Victoria L; Orsomando, Giuseppe; Angeletti, Carlo; Gilley, Jonathan; Lucci, Cristiano; Sanchez-Martinez, Alvaro; Whitworth, Alex; Conforti, Laura; Dajas-Bailador, Federico; Coleman, Michael

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Authors

Loreto, Andrea

Hill, Ciaran S

Hewitt, Victoria L

Orsomando, Giuseppe

Angeletti, Carlo

Gilley, Jonathan

Lucci, Cristiano

Publication Date

2020-02

Journal Title

Neurobiology of disease

ISSN

0969-9961

Volume

134

Pages

104678

Language

eng

Type

Article

This Version

Physical Medium

Print-Electronic

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Citation

Loreto, A., Hill, C. S., Hewitt, V. L., Orsomando, G., Angeletti, C., Gilley, J., Lucci, C., et al. (2020). Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.. Neurobiology of disease, 134 104678. https://doi.org/10.1016/j.nbd.2019.104678

Sponsorship

MRC (MC_UP_1501/1)

MRC (MC_UU_00015/6)

MEDICAL RESEARCH COUNCIL (MR/N004582/1)

Wellcome Trust (210904/Z/18/Z)

Identifiers

External DOI: https://doi.org/10.1016/j.nbd.2019.104678

This record's URL: https://www.repository.cam.ac.uk/handle/1810/299487