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dc.contributor.authorMilton, Amyen
dc.date.accessioned2019-12-05T00:30:16Z
dc.date.available2019-12-05T00:30:16Z
dc.date.issued2019-01en
dc.identifier.issn2046-1402
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/299524
dc.description.abstractFear is a highly adaptive emotion that has evolved to promote survival and reproductive fitness. However, maladaptive expression of fear can lead to debilitating stressor-related and anxiety disorders such as post-traumatic stress disorder. Although the neural basis of fear has been extensively researched for several decades, recent technological advances in pharmacogenetics and optogenetics have allowed greater resolution in understanding the neural circuits that underlie fear. Alongside conceptual advances in the understanding of fear memory, this increased knowledge has clarified mechanisms for some currently available therapies for post-traumatic stress disorder and has identified new potential treatment targets.
dc.format.mediumElectronic-eCollectionen
dc.languageengen
dc.publisherF1000 Research Ltd
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectHumansen
dc.subjectFearen
dc.subjectMemoryen
dc.subjectStress Disorders, Post-Traumaticen
dc.titleFear not: recent advances in understanding the neural basis of fear memories and implications for treatment development.en
dc.typeArticle
prism.publicationDate2019en
prism.publicationNameF1000Researchen
prism.volume8en
dc.identifier.doi10.17863/CAM.46598
dcterms.dateAccepted2019-11-13en
rioxxterms.versionofrecord10.12688/f1000research.20053.1en
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2019-01en
dc.contributor.orcidMilton, Amy [0000-0003-0175-9417]
dc.identifier.eissn2046-1402
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idMRC (MR/N02530X/1)


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International