Repository logo
 

Rerouting metabolism to activate macrophages.

Accepted version
Peer-reviewed

No Thumbnail Available

Type

Article

Change log

Authors

Murphy, Michael P 

Abstract

GPD2, the mitochondrial glycerol-3-phosphate dehydrogenase, contributes to the shift in core metabolism in macrophages activated during infection and during the transition to an alternatively activated phenotype during tissue repair.

Description

Keywords

Glycerol-3-Phosphate Dehydrogenase (NAD+), Glycolysis, Humans, Lipopolysaccharides, Macrophages, Oxidation-Reduction

Journal Title

Nature Immunology

Conference Name

Journal ISSN

1529-2908
1529-2916

Volume Title

20

Publisher

Springer Nature